Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Ubiquitin mediated proteolysis ID:04120
C=135; O=3; E=0.16; R=19.17; rawP=0.0005; adjP=0.0013
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000049759	NA	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	23327	ENSG00000049759
2	ENSG00000130939	NA	UBE4B	ubiquitination factor E4B	10277	ENSG00000130939
3	ENSG00000167986	NA	DDB1	damage-specific DNA binding protein 1, 127kDa	1642	ENSG00000167986

Database:KEGG pathway Name:Tight junction ID:04530
C=132; O=3; E=0.15; R=19.60; rawP=0.0005; adjP=0.0013
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000180104	NA	EXOC3	exocyst complex component 3	11336	ENSG00000180104
2	ENSG00000105357	NA	MYH14	myosin, heavy chain 14, non-muscle	79784	ENSG00000105357
3	ENSG00000105221	NA	AKT2	v-akt murine thymoma viral oncogene homolog 2	208	ENSG00000105221

Database:KEGG pathway Name:Protein processing in endoplasmic reticulum ID:04141
C=165; O=3; E=0.19; R=15.68; rawP=0.0009; adjP=0.0015
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000130939	NA	UBE4B	ubiquitination factor E4B	10277	ENSG00000130939
2	ENSG00000188021	NA	UBQLN2	ubiquilin 2	29978	ENSG00000188021
3	ENSG00000088833	NA	NSFL1C	NSFL1 (p97) cofactor (p47)	55968	ENSG00000088833

Database:KEGG pathway Name:Insulin signaling pathway ID:04910
C=138; O=2; E=0.16; R=12.50; rawP=0.0113; adjP=0.0141
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000182473	NA	EXOC7	exocyst complex component 7	23265	ENSG00000182473
2	ENSG00000105221	NA	AKT2	v-akt murine thymoma viral oncogene homolog 2	208	ENSG00000105221

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=3; E=1.31; R=2.29; rawP=0.1430; adjP=0.1430
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000184886	NA	PIGW	phosphatidylinositol glycan anchor biosynthesis, class W	284098	ENSG00000184886
2	ENSG00000049860	NA	HEXB	hexosaminidase B (beta polypeptide)	3074	ENSG00000049860
3	ENSG00000079459	NA	FDFT1	farnesyl-diphosphate farnesyltransferase 1	2222	ENSG00000079459

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).